Bioinformatics
Bioinformatics relies on techniques from applied mathematics, informatics, statistics, computer science, physics, chemistry, and biology to study biological composition, structure, function, and evolution at the molecular, cellular, and systems levels. It comprises all aspects of the gathering, storing, analysing, predicting, and disseminating the corresponding information. Graduate study in Bioinformatics at UCSF is a comprehensive track within the Integrative Program in Quantitative Biology and leads to a Ph.D. degree in Biological and Medical Informatics. The interdepartmental group consists of more than 20 faculty members drawn from a variety of fields. Approximately 30 students are enrolled in the program.
Training Program:
- Program Overview
- Core Curriculum
- Electives
- Seminars & Journal Club
- Academic Progression & Procedures
Graduate Group in Bioinformatics Website
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Heterotrimeric G protein (Protein Data Bank entry 1gg2) with the alpha subunit shown in green, the beta subunit in light blue, and the gamma subunit in brown.
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A crystal packing of the Thermus thermophilus chaperonin complex from Protein Data Bank entries 1we3 and 1wf. Structure (Camb). 2004 Aug;12(8):1471-80.
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Semliki forest virus. The bowl of smoke is a 9 angstrom resolution density map from electron cryo-microscopy. Mol Cell. 2000 Feb;5(2):255-66
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Powers RA, Morandi F, Shoichet BK. Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase. Structure 10, 1013-1023, 2002.
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The structure of the yeast ribosome determined by a combination of cryo- electron microscopy and comparative protein structure modeling. C. Spahn, R. Beckmann, N. Eswar, P. Penczek, A. Sali, G. Blobel, J. Frank. Cell 107, 361-372, 2001.
